Related Experiment Video
Updated: Jan 11, 2026
Novel Process for 3D Printing Decellularized Matrices
Published on: January 7, 2019
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Kumaresan Sakthiabirami1, Yeonwoo Park2, Seong Kyeong Jo1
1Department of Orthopedic Surgery, Konyang University Hospital, Daejeon, 35365, Republic of Korea.
None:
Tendon injuries pose significant clinical challenges due to complex structure and limited healing capacity. Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review summarizes the role of Extracellular Matrix (ECM), ongoing trends in the decellularization methods, as well as their integration with emerging technologies such as 3D printing, hybrid composite scaffold and hydrogels. Preclinical results and translational challenges are discussed. Overall, the review on the dECM-based scaffold strategies offer a compelling overview in understanding the tendon tissue engineering and their potential for clinical translation.
Related Concept Videos
01:26Extracellular Matrix
01:42The Extracellular Matrix
01:29The Extracellular Matrix
In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
Composition of the Extracellular Matrix
The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...