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Updated: Jan 11, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
HIV patient biopsychosocial complexity - Fixed or modifiable?
Kim Begley1, Don Smith1,2, Handan Wand3
1The Albion Centre, Surry Hills, NSW, Australia.
Abstract:
BackgroundBiopsychosocial comorbidities are common in chronic illnesses like HIV, often resulting in complex clinical presentations. The Clinical Complexity Rating Scale for HIV (CCRS-HIV) was developed to identify these factors. This study examined whether complexity, as measured by the CCRS-HIV, could change over time.MethodsPatients at The Albion Centre in Sydney were assessed at two time points (T1 and T2) using the CCRS-HIV. Changes in total and subscale scores were analysed, along with the odds of scoring in the complex range (40+ or 45+). The impact of age and time between assessments was also evaluated.ResultsResults showed a significant decrease in total complexity scores from T1 to T2, with improvements across four subscales-two psychological/behavioural, one social, and one biomedical. The proportion of complex cases declined, and participants were nearly twice as likely to be complex at T1 compared to T2. Longer intervals between assessments were linked to greater improvements, while age and sex had no effect.ConclusionsThese findings suggest that complexity in people living with HIV (PLHIV) is modifiable and support the CCRS-HIV as a valuable tool for screening and tracking changes in clinical complexity.
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