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Medical glaucoma management: what's new on the horizon?
Moon J Lee1,2, Ali Salimi1, Reza Razeghinejad1
1Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Introduction:
Glaucoma is a progressive optic neuropathy with medical therapies historically focusing on topical administration of drops. Thus, large barriers to effective treatment exist, including poor medication adherence and intolerance to local adverse effects. Emerging therapies are targeted toward circumventing some of these challenges and are now focused on newer topical formulations, sustained-release implants, and more recently gene therapy.
Areas Covered:
This review is intended to cover the existing and emerging medical therapies for glaucoma. It includes literature from searches from PubMed, published abstracts as well as press releases and company communications. Included articles were published from 1954 to 2025.
Expert Opinion:
Several new medical therapies for glaucoma are currently in development. Emerging pharmacological and drug delivery methods have the potential to provide longer-lasting therapeutic and potentially preventative treatments for individuals with glaucoma. Further investigation is needed to determine the long-term clinical implications of such treatments for glaucoma.
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