Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

3.8K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.8K
External Female Genitals01:15

External Female Genitals

28.2K
The vulva encompasses the external structures of the female reproductive system. At the forefront is the monpubis, a cushion of fatty tissue atop the pubic bone. Once puberty sets in, this area typically grows hair. Extending from just behind the mons pubis are the labia majora (labia = 'lips'; majora = 'larger'), which are larger skin fs olds coated with hair. Nestled within are the labia minora (labia = 'lips'; minora = 'smaller'), which are thinner, more...
28.2K
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

9.3K
Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
9.3K
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

6.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
6.1K
Uterus and Cervix01:18

Uterus and Cervix

4.2K
The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...
4.2K
Skin Cancer01:30

Skin Cancer

5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Saliva vs Plasma in Liquid Biopsy Sampling for Head and Neck Cancer: A Comparative Study.

Clinical chemistry·2026
Same author

Gynecologic Cancers: Cervical Cancer.

FP essentials·2025
Same author

Gynecologic Cancers: Endometrial Cancer.

FP essentials·2025
Same author

Gynecologic Cancers: Ovarian Cancer.

FP essentials·2025
Same author

Extracellular Matrix-MYCAF Signatures Correlate with Resistance to Neoadjuvant aPD-L1 Immune Checkpoint Inhibition with Durvalumab + Metformin in HPV+ HNSCC.

Clinical cancer research : an official journal of the American Association for Cancer Research·2025
Same author

Bridging the gap: associations of provider enrollment in OKCAPMAP with social deprivation, child abuse, and barriers to access in the state of Oklahoma, USA.

Journal of osteopathic medicine·2025

Related Experiment Video

Updated: Jan 11, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

8.6K

Gynecologic Cancers: Vulvar Cancer.

Bindusri Paruchuri1, Amanda Miller1

  • 1Department of Family Medicine at the University of Tennessee Health Science Center, College of Medicine- Nashville, TN.

FP Essentials
|November 18, 2025
PubMed
Summary
This summary is machine-generated.

Vulvar cancer is increasingly affecting younger women due to human papillomavirus. Early detection and risk factor management by family physicians are crucial for improved survival rates.

More Related Videos

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.6K
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
10:21

A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions

Published on: March 3, 2023

2.2K

Related Experiment Videos

Last Updated: Jan 11, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

8.6K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.6K
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
10:21

A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions

Published on: March 3, 2023

2.2K

Area of Science:

  • Gynecology
  • Oncology
  • Public Health

Background:

  • Vulvar cancer, a rare gynecologic malignancy, was historically associated with postmenopausal women.
  • Recent data indicate a rise in premenopausal vulvar cancer incidence, linked to human papillomavirus (HPV) infection.
  • Family physicians serve as primary care points for reproductive-age individuals, highlighting their role in early intervention.

Purpose of the Study:

  • To emphasize the critical role of family physicians in recognizing and managing vulvar cancer.
  • To advocate for early detection strategies and risk factor modification, including HPV vaccination.
  • To reduce diagnostic delays and improve patient outcomes for vulvar cancer.

Main Methods:

  • Review of epidemiologic data on vulvar cancer trends.
  • Emphasis on the importance of routine gynecologic examinations including perineal visualization.
  • Discussion of risk factor identification (e.g., lichen sclerosus) and diagnostic procedures like biopsy.
  • Outline of treatment modalities based on cancer stage (e.g., vulvectomy, radiation, chemotherapy).

Main Results:

  • Vulvar cancer diagnosis is often delayed by approximately two years from initial presentation.
  • Human papillomavirus infection is a significant factor in the increasing rates among younger women.
  • Early identification and management of vulvar pathology and risk factors are essential for timely diagnosis and treatment.

Conclusions:

  • Enhanced physician awareness and patient education are vital for reducing diagnostic delays in vulvar cancer.
  • Routine screening and prompt management of suspicious lesions can significantly improve patient survival.
  • Comprehensive survivorship care tailored to individual gynecologic and general health needs is recommended.