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Related Experiment Video

Updated: Jan 11, 2026

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Published on: June 13, 2025

Neurophysiology: Mapping brain activity on a global scale.

Timothy O'Leary¹

¹Department of Engineering, University of Cambridge, Trumpington Street, Cambridge CB2 1PZ, UK.

Current Biology : CB

|November 18, 2025

Summary

This summary is machine-generated.

Scientists mapped neural activity in a mammalian brain at cellular resolution. They discovered brain signals for intentions and beliefs appear before actions.

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Area of Science:

Neuroscience
Systems Neuroscience
Computational Neuroscience

Background:

Understanding the neural basis of cognition requires mapping brain activity.
Previous studies lacked the resolution to observe cellular-level neural dynamics across the entire brain.

Purpose of the Study:

To conduct the first global, cellular-resolution survey of neural activity in a mammalian brain.
To identify the spatiotemporal dynamics of neural signals related to intentions and beliefs.

Main Methods:

Coordinated international laboratory experiments.
High-resolution neural activity recording techniques.
Analysis of neural signals across distributed brain regions.

Main Results:

Achieved the first cellular-resolution neural activity map of a mammalian brain.
Identified widespread neural signals associated with intentions and beliefs.
Demonstrated that these cognitive signals precede overt behavioral actions.

Conclusions:

Global, coordinated efforts can achieve unprecedented neuroscience research milestones.
Neural correlates of intentions and beliefs are distributed and anticipatory.
This work provides a foundational dataset for understanding cognitive processes in mammals.