[Thoracoscopic Wedge Resection of Pulmonary Carcinoma with Myelofibrosis while Managing Thrombocytopenia:Report of a...

The case is a woman in her 70s. She was scheduled to receive a hematopoietic stem cell transplant for myelofibrosis with thrombocytopenia. Chest computed tomography (CT) examination showed a part solid lesion in the lower lobe of the left lung, raising suspicion of pulmonary microinvasive adenocarcinoma. Following preoperative platelet transfusion, the count increased up to 11.1×104/μl, and she underwent thoracoscopic wedge resection of the lung lesion. Pathological examination revealed in situ adenocarcinoma. The chest tube was removed 3 days later at a platelet count of 5.1×104/μl and she was discharged on postoperative day 6. The count returned to baseline as early as postoperative 5 or 6 day. We require predictive strategies for the perioperative management of thrombocytopenia because patients with bone marrow failure have a shorter platelet lifespan.