Consanguineous marriages and low birth weight mediating role of antenatal care visits
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View abstract on PubMed
Summary
This summary is machine-generated.Consanguineous marriage in Pakistan is linked to low birth weight (LBW), partly due to fewer antenatal care (ANC) visits. Improving ANC access for these communities can reduce LBW risks.
Area Of Science
- Public Health
- Genetics
- Maternal and Child Health
Background
- Low birth weight (LBW) is a major public health issue in Pakistan, contributing to neonatal mortality.
- Consanguineous marriages are common in Pakistan and associated with adverse birth outcomes.
- The role of antenatal care (ANC) in mediating the link between consanguinity and LBW is not well understood.
Purpose Of The Study
- To investigate whether antenatal care (ANC) visits mediate the association between consanguineous marriage and low birth weight (LBW) in Pakistan.
Main Methods
- Cross-sectional study using data from the 2017-18 Pakistan Demographic and Health Survey (PDHS) of 14,465 live births.
- Generalized Structural Equation Modeling (GSEM) analyzed the relationship between consanguineous marriage (independent variable), ANC visits (mediating variable), and LBW (dependent variable).
- Adjusted for maternal age, region, residence, household wealth, and working status; used 2000 bootstrap replications.
Main Results
- Consanguineous marriage was associated with reduced likelihood of adequate ANC visits (β=-0.015, p<0.001).
- Adequate ANC visits were strongly associated with a reduced risk of LBW (β=-0.403, p<0.001).
- A significant indirect effect of consanguineous marriage on LBW via reduced ANC utilization was found (β=0.0062, p=0.001), alongside a direct positive association (β=0.0173, p=0.035), indicating partial mediation.
Conclusions
- Consanguineous marriage increases LBW risk in Pakistan, partly through reduced antenatal care utilization.
- Both behavioral (lower ANC uptake) and biological (genetic) factors likely contribute to adverse outcomes in consanguineous unions.
- Interventions should focus on increasing ANC access and utilization in at-risk communities, alongside genetic counseling and promoting women's healthcare autonomy.
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