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Expansion of Two-dimension Electrospun Nanofiber Mats into Three-dimension Scaffolds

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Hierarchical Micro/Nano-Structured Biomaterials for Wound Healing.

Minhui Lu¹, Zhiqiang Luo¹, Hanxu Chen¹

¹Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

Research (Washington, D.C.)

|November 19, 2025

Summary

This summary is machine-generated.

Hierarchical biomaterials with micro/nano structures offer advanced wound healing solutions. These materials possess antibacterial and antioxidant properties, significantly improving treatment outcomes for various wounds.

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Area of Science:

Biomedical Engineering
Materials Science
Regenerative Medicine

Background:

Wound healing is a universal biomedical challenge.
Traditional dressings like gauze are limited.
Hierarchical biomaterials offer advanced wound treatment capabilities.

Purpose of the Study:

To review hierarchical biomaterials with micro/nano structures for wound treatment.
To discuss fabrication strategies and characteristics of these advanced materials.
To highlight their applications in diverse wound types.

Main Methods:

Literature review of hierarchical biomaterials for wound healing.
Analysis of fabrication techniques for micro/nano structured biomaterials.
Discussion of biomaterials with antibacterial, antioxidant, and oxygen-releasing properties.

Main Results:

Hierarchical biomaterials demonstrate enhanced wound healing promotion.
Specific curative features include antibacterial, antioxidant, and oxygen supply.
These materials show promise across various wound applications.

Conclusions:

Hierarchical biomaterials represent a significant advancement in wound care.
Further research into their development and application is warranted.
These materials hold potential for future wound treatment strategies.