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A multidisciplinary approach to establishing clozapine in a patient with schizophrenia and comorbid ASD: a case
Madelaine Bridges1, Agostina Secchi1, Eromona Whiskey2,3,4
1Kent and Medway NHS and Social Care Partnership Trust, Hermitage Lane, Maidstone, Kent, UK.
Background:
There is substantial symptom overlap in psychosis and autism spectrum disorder (ASD) and co-morbidity is common. In addition, antipsychotic response may be moderated by the co-occurrence. Individuals with ASD may be at greater risk of some clozapine adverse effects and occasionally, its use may be contra-indicated.
Case Presentation:
We present the case of a patient with ASD with psychosis unresponsive to multiple antipsychotics, but extra precaution was required with clozapine.
Conclusion:
A multidisciplinary approach is required to establish clozapine in a patient with schizophrenia and ASD.
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