Photoinduced Multicomponent Sulfonylsulfination of Alkenes via Aromatization-Driven Deconstructive and Radical-Polar
Wenchao Gao1, Yong Teng1, Kexin Huang2
1Engineering Technology Research Centre of Henan Province for Photo- and Electrochemical Catalysis, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, Henan, P. R. China.
Abstract:
A facile methodology, consisting of photoenabled multicomponent coupling of alkenes, spiro-dihydroquinazolinones, and DABSO, is described. This protocol features deconstruction-cyclization efficiency, functional group tolerance, and mild and sustainable conditions, readily producing a series of valuable sulfonylsulfinated derivates with SIV and SVI centers in moderate to high yields. A photoinduced aromatization-mediated deconstructive process and a radical-polar crossover cyclization process involving twofold insertion of SO2 are proposed in this transformation.
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