Determinants of invasive ventilation in infants with acute bronchiolitis: an observational study of pre-hospital and in-hospital treatments
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View abstract on PubMed
Summary
This summary is machine-generated.Younger infants with acute bronchiolitis requiring invasive ventilation had higher severity scores and atelectasis. This study highlights factors influencing mechanical ventilation needs and medication use in hospitalized infants.
Area Of Science
- Pediatrics
- Respiratory Medicine
- Critical Care
Background
- Acute bronchiolitis is a common respiratory infection in infants.
- Invasive ventilation is a critical intervention for severe cases.
- Understanding factors associated with ventilation is crucial for timely management.
Purpose Of The Study
- To identify factors linked to invasive ventilation in infants with acute bronchiolitis.
- To analyze treatments administered before and during hospitalization for these infants.
Main Methods
- Retrospective observational study of 266 infants with acute bronchiolitis.
- Multivariate logistic regression to determine factors associated with invasive ventilation.
- Prais-Winsten regression for temporal trend analysis.
Main Results
- 6% of infants required intubation.
- Younger age, higher Wood-Downes-Ferres scores, and atelectasis were associated with invasive ventilation.
- Bronchodilator use increased, while corticosteroid use decreased before/after admission.
Conclusions
- Younger age, atelectasis, and higher admission severity scores predict invasive ventilation need.
- Frequent medication administration before and during hospitalization was noted.
- Clinical protocols should consider these factors and aim to reduce pre-hospitalization medication use.
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