Retrospective SPECT-MR fusion: a great problem-solving tool

Images obtained from different imaging modalities serve different radiological purposes, some providing anatomical details while others provide functional and physiological insights. Seamless integration of these images into a single image can yield a synergistic representation of these details, enhancing diagnostic accuracy and clinical decision-making. This is best achieved by retrospectively fusing the images using specialized software platforms that align and co-register multimodal datasets. Our review article delves into the fundamental principles underpinning this technique and provides a step-by-step guide for performing image fusion. Additionally, we explore the clinical implications of SPECT-MR fusion, its advantages over conventional standalone imaging and provide the potential future advances in this area.