Related Experiment Video For Barrett’s esophagus
Updated: Jan 10, 2026

Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion
Published on: July 6, 2022
Emerging Challenges of Postendoscopy Esophageal Adenocarcinoma and Postendoscopy Esophageal Neoplasia
Sridevi K Pokala1, Jesper Lagergren2, Sachin Wani1
1Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Center, Aurora, CO, USA.
Abstract:
Post-endoscopy esophageal neoplasia (PEEN) and post-endoscopy esophageal adenocarcinoma (PEEC) comprise a significant component of all Barrett's esophagus-related neoplasia diagnoses and rates of PEEN/PEEC may be rising. PEEN/PEEC occur primarily due to missed lesions or rapidly progressive disease. Root-cause analysis should be performed for cases and best practices should be implemented to decrease PEEN/PEEC rates - the most important intervention is a high-quality endoscopic exam. Future efforts should determine the role of biomarkers in identifying individuals at high risk of neoplastic progression, develop additional tissue-sampling techniques to reduce missed lesions, and improve education regarding the principles of a high-quality endoscopic examination.
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