Pennsieve: A Collaborative Platform for Translational Neuroscience and Beyond

The exponential growth of neuroscientific data necessitates platforms for data management and multidisciplinary collaboration. In this paper, we introduce Pennsieve, an open-source, cloud-based scientific data management platform that supports findable, accessible, interoperable, and reusable (FAIR) data sharing. It has integrated tools for data visualization, processing, and peer-reviewed data publishing that promote collaborative research and high-quality datasets optimized for downstream analysis, both in the cloud and on-premises. Pennsieve welcomes data submissions from individual investigators and small labs through entire consortia. It already serves more than 80 research groups worldwide and forms the core for several large-scale, interinstitutional projects and major government neuroscience research programs. Pennsieve stores over 125 TB of scientific data, with 35 TB of data publicly available in more than 350 high-impact datasets. By facilitating scientific data management, discovery, and analysis, Pennsieve fosters a robust and collaborative research ecosystem for neuroscience and beyond.