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Solid pseudopapillary neoplasm of the pancreas: A case report
Marian Bakos1, Stefan Durdik2, Milan Dubaj1
1Department of Surgery, Faculty Hospital Nitra, Nitra, Slovakia.
Medicine
|November 20, 2025
Summary
Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor with a good prognosis. This case highlights diagnostic challenges and the benefits of laparoscopic surgery for SPN treatment.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare, low-grade tumor with a favorable prognosis.
- First described in 1959, SPN diagnosis can be challenging, especially differentiating it from other pancreatic neoplasms like neuroendocrine tumors.
Purpose of the Study:
- To report a case of incidentally discovered pancreatic SPN in a young adult.
- To discuss the diagnostic considerations and surgical management of pancreatic SPN.
Main Methods:
- A 28-year-old male presented with suspected diverticulitis, leading to an incidental finding of a pancreatic lesion on CT scan.
- Diagnostic workup included imaging and cytological analysis, followed by surgical intervention.
Main Results:
- An incidental pancreatic lesion was identified, initially suspected to be a tumor near the splenic artery.
- Cytological analysis suggested a neuroendocrine tumor, but the final diagnosis post-surgery was confirmed as SPN of the pancreas.
- Laparoscopic pancreatectomy was performed, offering benefits over traditional laparotomy.
Conclusions:
- Differentiating SPN from other pancreatic tumors can be difficult based on initial cytology or biopsy.
- Laparoscopic pancreatectomy is a viable surgical option for SPN, associated with reduced blood loss and shorter recovery times.
- SPN generally carries a good prognosis following complete surgical excision, even with local invasion or metastases.
