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Piloting a Point-of-Care Drug-Checking Service at Syringe Service Programs in New York City
Yarelix Estrada1, Hannah L Helmy1, Ashly E Jordan1
1New York City Department of Health and Mental Hygiene, Bureau of Alcohol and Drug Use, New York, NY, USA.
Substance Use & Addiction Journal
|November 20, 2025
Summary
New York City
Area of Science:
- Public Health
- Harm Reduction
- Drug Policy
Background:
- Drug checking is a vital harm reduction strategy for safer drug use.
- High overdose rates necessitate innovative interventions for unregulated drug supplies.
- The NYC DOHMH launched a pilot program for point-of-care drug checking.
Purpose of the Study:
- To assess the feasibility and acceptability of point-of-care drug checking.
- To provide actionable information on drug contents to people who use drugs (PWUD).
- To evaluate the impact of drug checking on harm reduction behaviors.
Main Methods:
- Drug checking services were implemented at 6 sites using test strips and spectrometers.
- Staff received training on drug analysis, interpretation, and harm reduction education.
- Participant data and drug sample information were collected via a REDCap database.
Main Results:
- Over 1600 samples were analyzed from November 2021 to December 2023.
- Fentanyl was present in 95% of samples sold as opioids; xylazine in 35%.
- Over 50% of participants intended to change their drug use behavior post-testing.
Conclusions:
- Point-of-care drug checking is feasible and acceptable for health departments and PWUD.
- Drug checking can potentially influence behavioral intentions for safer drug use.
- Robust training, appropriate technology, and secondary testing are crucial for implementation.

