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Physiologic Medial Meniscal Extrusion With Loading and Flexion Detected by Ultrasound
Maria E Dey Hazra1,2, Rony-Orijit Dey Hazra1,3, Amelia Kruse1,4
1The Steadman Philippon Research Institute, Vail, Colorado, USA.
Orthopaedic Journal of Sports Medicine
|November 20, 2025
Summary
Ultrasound assessment of medial meniscal extrusion (MME) is more valuable under loaded conditions and varying knee flexion angles. Unloaded, supine MME may not accurately reflect in-vivo meniscal behavior during daily activities.
Area of Science:
- Orthopedics
- Radiology
- Biomechanics
Background:
- Medial meniscal extrusion (MME) is a risk factor for knee osteoarthritis.
- Current ultrasound protocols for MME vary in flexion angles and weightbearing, complicating interpretation.
- Understanding MME's response to loading and position is crucial.
Purpose of the Study:
- To investigate the influence of loading and knee flexion on medial meniscal extrusion (MME) using ultrasound.
- To compare MME across different stances (supine, single-leg, double-leg) and flexion angles (neutral, 20°, 45°).
Main Methods:
- Descriptive laboratory study involving 21 asymptomatic volunteers.
- Ultrasound imaging of the medial meniscus in coronal plane.
- Real-time knee angles measured with motion capture during supine and weightbearing positions at varying flexion angles.
Main Results:
- MME was significantly lower in supine (1.1) compared to single-leg (1.3) and double-leg (1.3) stances (P < .0001).
- Increasing knee flexion significantly reduced MME, with the lowest extrusion at 45° (1.0) compared to neutral (1.4) (P < .0001).
- No significant difference in MME was found between right and left legs.
Conclusions:
- Unloaded, supine ultrasound examinations of MME may have limited clinical value.
- Loaded ultrasound assessments better represent meniscal biomechanics during activities of daily living.
- Assessing physiologic meniscal behavior aids in managing meniscal pathology.

