Related Experiment Video
Updated: Jun 14, 2026

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
Published on: June 28, 2018
Evidence-Based Practices in the Cardiac Catheterization Laboratory: Invasive Epicardial Coronary Physiologic
Insights
This review clarifies evidence-based practices for invasive epicardial coronary physiologic assessment. It addresses common misconceptions in evaluating intermediate coronary lesions, promoting accurate hemodynamic significance interpretation.
Area of Science:
- Cardiology
- Interventional Cardiology
- Physiology
Background:
- Invasive epicardial coronary physiologic assessment is crucial for evaluating intermediate coronary lesions.
- Guidelines recommend its use, yet misconceptions persist.
- Distinguishing evidence-based practice from tradition is vital.
Purpose of the Study:
- To review and highlight evidence-based practices in coronary physiologic assessment.
- To address and validate or refute common clinical misconceptions.
- To promote accurate hemodynamic significance evaluation.
Main Methods:
- Literature review of current evidence.
- Analysis of common clinical practices and traditions.
- Comparison of practices against established guidelines and evidence.
Main Results:
- Identification of key evidence-based techniques for coronary physiologic assessment.
- Debunking of persistent non-evidence-based traditions.
- Validation of specific clinical practices based on hemodynamic significance.
Conclusions:
- Adherence to evidence-based practices improves diagnostic accuracy.
- Correcting misconceptions enhances patient care for intermediate coronary lesions.
- Standardized, evidence-based assessment is recommended for optimal outcomes.
Abstract:
Invasive epicardial coronary physiologic assessment is increasingly performed to evaluate the hemodynamic significance of intermediate coronary lesions and is recommended by guideline committees. Whereas much of the practice in coronary physiologic assessment is based on evidence, some non-evidence-based traditions and misconceptions persist. The aim of this review is to highlight evidence-based practice in invasive epicardial coronary physiologic assessment and to refute or validate common elements of clinical practice.
Related Concept Videos
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization II: Right Heart Catheterization
Cardiac Catheterization III: Left Heart Catheterization
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies

