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Updated: Aug 1, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
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Thalamic Stimulation Induced Changes in Network Connectivity and Excitability in Epilepsy

Nicholas M Gregg1, Gabriela Ojeda Valencia2, Tereza Pridalova1

  • 1Department of Neurology, Mayo Clinic, Rochester, MN.

Annals of Neurology
|November 20, 2025
PubMed
Summary

Deep brain stimulation (DBS) and brain stimulation evoked potentials (BSEPs) during sEEG map epilepsy networks. Longer DBS trials modulated network excitability, while shorter trials reduced seizure activity, advancing biomarker-informed neuromodulation.

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