Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Overview Of Cell Separation And Isolation

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Structure-functional characterization of Lactococcus AbiA phage defense system.

Nucleic acids research·2024

Same author

Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.

Nucleic acids research·2022

Same author

The Pet127 protein is a mitochondrial 5'-to-3' exoribonuclease from the PD-(D/E)XK superfamily involved in RNA maturation and intron degradation in yeasts.

RNA (New York, N.Y.)·2022

Same author

Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.

Nucleic acids research·2019

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

mRNA Interactome Capture from Plant Protoplasts

mRNA Interactome Capture from Plant Protoplasts

Published on: July 28, 2017

Phase-Separating Proteins in Plants and Methods Used to Study Them

Marta Gapińska¹

¹Zakład Biologii Systemów, Wydział Biologii, Uniwersytet Warszawski.

Postepy Biochemii

|November 20, 2025

Summary

Membraneless biomolecular condensates, formed by liquid-liquid phase separation (LLPS), are crucial for plant stress responses. This review covers methods to study these structures and the proteins involved in plant LLPS.

More Related Videos

Identification of Post-translational Modifications of Plant Protein Complexes

Identification of Post-translational Modifications of Plant Protein Complexes

Published on: February 22, 2014

Fluorescence Activated Cell Sorting of Plant Protoplasts

Fluorescence Activated Cell Sorting of Plant Protoplasts

Published on: February 18, 2010

Related Experiment Videos

Last Updated: Jan 10, 2026

mRNA Interactome Capture from Plant Protoplasts

mRNA Interactome Capture from Plant Protoplasts

Published on: July 28, 2017

Identification of Post-translational Modifications of Plant Protein Complexes

Identification of Post-translational Modifications of Plant Protein Complexes

Published on: February 22, 2014

Fluorescence Activated Cell Sorting of Plant Protoplasts

Fluorescence Activated Cell Sorting of Plant Protoplasts

Published on: February 18, 2010

Area of Science:

Cell Biology
Molecular Biology
Plant Science

Background:

Cells require compartmentalization for efficient biochemical processes.
Membraneless biomolecular condensates, formed via liquid-liquid phase separation (LLPS), provide dynamic functional areas.
LLPS is increasingly recognized as vital for plant stress response.

Purpose of the Study:

To review current methodologies for studying macromolecular condensates in plants.
To explore the roles of proteins undergoing LLPS in plant stress responses.

Main Methods:

Review of existing literature on condensate research methods.
Analysis of studies investigating protein function in plant LLPS.

Main Results:

Various techniques exist to study biomolecular condensates.
Proteins involved in LLPS play significant roles in how plants perceive and react to environmental stresses.

Conclusions:

Understanding LLPS and its associated proteins is key to deciphering plant stress adaptation.
Further research into condensate dynamics can reveal novel mechanisms for crop improvement.