Efficacy and safety of ureteroscopy in children with lower pole renal stones : a machine learning predictive model from the EAU section of endourology
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Machine learning accurately predicts outcomes for pediatric kidney stone treatment using flexible ureteroscopy. Key factors like stone number and burden help stratify risk for incomplete clearance.
Area Of Science
- Pediatric Urology
- Minimally Invasive Surgery
- Machine Learning in Medicine
Background
- Pediatric kidney stone disease, especially lower pole (LP) calculi, poses treatment challenges.
- Flexible ureteroscopy with laser lithotripsy (fURSL) is a common treatment, but outcomes vary.
- Predicting surgical success for pediatric LP stones requires further investigation.
Purpose Of The Study
- To apply machine learning (ML) models for predicting surgical outcomes in pediatric patients undergoing fURSL.
- To identify key preoperative predictors of incomplete stone clearance in lower pole calculi.
Main Methods
- Retrospective analysis of 91 pediatric patients (≤16 years) with isolated LP stones undergoing fURSL.
- Development and evaluation of 15 ML models, including Random Forest and Gradient Boosting.
- Utilized SHAP values for interpretability to identify significant predictors.
Main Results
- Random Forest model achieved 80.95% validation accuracy and 76.67% F1-score.
- Stone number, total stone burden, age, and operative time were identified as top predictors of outcome.
- fURSL demonstrated safety and efficacy, though incomplete stone clearance was noted.
Conclusions
- ML models show strong predictive performance for fURSL outcomes in pediatric kidney stone patients.
- ML can aid in preoperative risk stratification for lower pole calculi.
- Further validation and prospective studies are needed to refine ML tools for clinical application.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...