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Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing

Jessica J Lu1,2, Giuseppe Deganutti3, Miaomiao Li1,2

  • 1Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.

Proceedings of the National Academy of Sciences of the United States of America
|November 20, 2025
PubMed
Abstract

Keywords:
cryo-EMligand selectivitypituitary adenylate cyclase-activating polypeptide 1 receptorsplice variants

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