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Related Experiment Video

Updated: Jan 10, 2026

Performing Intracochlear Electrocochleography During Cochlear Implantation
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Electrocochleography for Monitoring Hearing Preservation During Cochlear Implantation.

Raphael R Andonie1,2, Christofer Bester3, Sudanthi Wijewickrema3

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, Bern University Hospital, Bern, Switzerland.

JAMA Otolaryngology-- Head & Neck Surgery
|November 20, 2025
PubMed
Summary

Automated intraoperative electrocochleography can predict hearing preservation during cochlear implantation. Persistent cochlear microphonic events near insertion end correlate with hearing loss, guiding surgical decisions.

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Area of Science:

  • Otolaryngology
  • Audiology
  • Biomedical Engineering

Background:

  • Residual hearing in cochlear implant candidates can be lost during surgery.
  • Intraoperative electrocochleography (ECoG) shows promise for monitoring residual hearing but lacks real-time analysis and is subject to interpretation variability.

Purpose of the Study:

  • To determine if automated analysis of intraoperative cochlear microphonic (CM) amplitude decreases (events) predicts hearing preservation.
  • To evaluate if other ECoG features can enhance predictive performance for hearing preservation.

Main Methods:

  • A multicenter, cross-sectional study of 112 adult cochlear implant patients using the Slim Straight Electrode array.
  • Intraoperative ECoG and impedance data were collected in real-time, with audiometric follow-up at 3 months.
  • Analysis focused on CM events (magnitude, location, persistence) and their association with hearing preservation.

Main Results:

  • Persistent CM events near the end of insertion were significantly associated with hearing loss (aORs > 31.58).
  • Rising auditory nerve neurophonic:CM amplitude ratio correlated with better hearing preservation (24.4% difference).
  • Stable CM phase also trended towards better hearing preservation (20.9% difference).

Conclusions:

  • Automated intraoperative ECoG is feasible for predicting hearing preservation during cochlear implantation.
  • Persistent CM events indicate a risk of hearing loss.
  • Further development of real-time feedback systems using ECoG features is warranted to guide surgical techniques and improve outcomes.