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Updated: Jan 10, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Simplified Meal Bolus Strategies with Control-IQ+ Automated Insulin Delivery Are Safe and Effective in Adults with
Carol J Levy1, Lauren Kanapka2, Sue A Brown3
1Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Objective:
To characterize simplified meal bolus strategies in adults with insulin-treated type 2 diabetes using automated insulin delivery (AID).
Research Design And Methods:
In the 2IQP study, a 13-week randomized, controlled trial comparing Control-IQ+ AID to continuation of pre-study insulin regimen with continuous glucose monitoring, 201 participants in the AID arm were classified by meal bolus strategy. Glycemic outcomes were compared to baseline.
Results:
68 participants' meal bolus strategies (33.8%) were classified as Carbohydrate Counting, 79 (39.3%) were classified as Preset Carbohydrate Amounts, 27 (13.4%) were classified as Fixed Insulin Doses, and 27 (13.4%) as Other Methods. All bolus strategies were associated with similar, significant improvements in HbA1c from baseline: -0.9% for Carbohydrate Counting (P < 0.001), -1.1% for Preset Carbohydrate Amounts (P < 0.001), -0.8% for Fixed Insulin Doses (P < 0.001), and -0.9% for Other Methods (P = 0.003). Hypoglycemia rates were low at baseline and remained low for all bolus strategies. As participants gained experience with the Control-IQ+ AID system, more participants opted to use a simplified bolus strategy in the second half of the study compared with the first half (63% vs. 52%).
Conclusion:
Simplified bolus strategies worked well for adults with type 2 diabetes using Control-IQ+ in the 2IQP trial. All bolus strategies led to substantial HbA1c improvements, without safety concerns.
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