Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Infertility in Males

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating large language models for abstract evaluation tasks: an empirical study.

Frontiers in research metrics and analytics·2026

Same author

The pediatric AI readiness framework: bridging evidence to practice in pediatric artificial intelligence.

Frontiers in artificial intelligence·2026

Same author

Evaluating Whether Icons and Visual Elements Help or Hinder Understanding of Key Information for Research Studies: Results From a Randomized Trial.

Health literacy research and practice·2026

Same author

An AI-based chatbot to support health-related social needs among pediatric primary care population: Protocol for a pilot randomized controlled trial.

PloS one·2026

Same author

Colorectal Cancer Screening and Health-Related Social Needs in a National Sample of US Adults.

JAMA network open·2026

Same author

Toward trustworthy chatbots: a protocol for red teaming for health related conversations.

Scientific reports·2026

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

Mouse Round Spermatid Injection

Mouse Round Spermatid Injection

Published on: January 26, 2024

Implementing a User-Centered Design to Develop a Web-Based Sperm Banking Decision Tool for Adolescent Males with

Megan M Griffith¹, Emre Sezgin^1,2, Tanvi Karkare¹

¹The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.

Journal of Adolescent and Young Adult Oncology

|November 20, 2025

Summary

A new tool, the Family-centered Adolescent Sperm banking values clarification Tool (FAST), was developed for adolescent males with cancer to aid fertility decisions. This user-centered tool was found to be easy to navigate and useful for families.

Keywords:

adolescent cancer digital health sperm banking usability testing user-centered design

More Related Videos

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

Related Experiment Videos

Last Updated: Jan 10, 2026

Mouse Round Spermatid Injection

Mouse Round Spermatid Injection

Published on: January 26, 2024

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

Area of Science:

Oncology
Reproductive Medicine
Adolescent Health

Background:

Male childhood cancer survivors frequently face fertility impairment due to cancer treatments.
Regret over missed sperm banking opportunities is common among survivors.
A lack of decision-making tools for adolescent males with cancer exacerbates this issue.

Purpose of the Study:

To develop, test, and adapt the Family-centered Adolescent Sperm banking values clarification Tool (FAST).
To utilize an iterative, user-centered design involving male adolescents with cancer and their caregivers.
To gather feedback from clinicians and community partners for tool refinement.

Main Methods:

Ten families (9 adolescents, 16 caregivers) participated.
Participants completed the FAST, a semi-structured interview, and the System Usability Scale (SUS).
Feedback was used for adaptations, documented using the Framework for Reporting Adaptations and Modifications-Expanded.

Main Results:

Forty-three adaptations were made to the FAST based on user feedback.
The median completion time for the FAST was 5 minutes and 37 seconds.
The FAST achieved a high mean SUS score of 84.60, indicating excellent usability.

Conclusions:

The FAST was successfully developed, usability-tested, and adapted into a web-based format.
Adolescents and caregivers found the FAST easy to navigate and useful.
Web-based tools like the FAST can enhance sperm banking decision-making and improve satisfaction with fertility counseling outcomes for young males with cancer.