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FBFormer: interventional ultra-sparse CT reconstruction with image prior using feature back-projection and
Shankui Li1,2, Yibo Pei1,2, Yanyan Liu2
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.
Physics in Medicine and Biology
|November 20, 2025
Summary
This study introduces FBFormer, a new method using intraoperative X-ray images to reconstruct CT scans, significantly reducing patient radiation exposure during interventional procedures.
Area of Science:
- Medical Imaging
- Computer Vision
- Radiology
Background:
- CT-guided interventions are crucial but involve high radiation doses.
- Prolonged scan times and numerous images contribute to patient radiation exposure.
Purpose of the Study:
- To develop an alternative to intraoperative CT guidance using X-ray imaging.
- To reconstruct interventional CT by integrating preoperative images with intraoperative X-ray data.
- To reduce radiation exposure while maintaining reconstruction quality.
Main Methods:
- Feature back-projection Transformer (FBFormer) framework for tomographic data reconstruction.
- Utilizes ultra-sparse intraoperative X-ray images (less than 10 views).
- Employs a mixed UNet and PVT encoder for feature extraction and a feature back-projection module for 2D-3D conversion.
Main Results:
- FBFormer demonstrates effectiveness on simulated 4DCT and clinical validation datasets.
- Achieves superior reconstruction performance metrics compared to other methods.
- Outperforms existing compelling reconstruction techniques.
Conclusions:
- The FBFormer framework can significantly reduce radiation exposure in interventional procedures.
- Enhances clinical reliability of interventional CT reconstruction from sparse X-ray projections.
- Integrates image priors and a geometrically consistent feature back-projection module for high-quality results.
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