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Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
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Distinct multidimensional anger profiles predict current and long-term chronic pain outcomes.
Marine Granjon1, Noel Vest2, Sean C Mackey3
1Institute of Biomedical and Oral Research, Hebrew University of Jerusalem, Israel; Department of Psychology, University of Innsbruck, Austria.
The Journal of Pain
|November 20, 2025
Summary
Chronic pain patients exhibit distinct anger profiles, with higher anger and perceived injustice linked to worse pain outcomes. Identifying these profiles can improve risk stratification and personalized pain care.
Area of Science:
- Psychology
- Pain Medicine
- Health Services Research
Background:
- Anger is common in chronic pain (CP), often worsening distress and disability.
- Understanding the interplay of anger dimensions is crucial for effective CP management.
- Current research often overlooks the multifaceted nature of anger in chronic pain.
Purpose of the Study:
- To identify distinct anger profiles in individuals with CP using latent profile analysis (LPA).
- To examine the association of these anger profiles with pain outcomes cross-sectionally and longitudinally.
- To determine if anger profiles predict pain outcomes beyond anxiety and depression.
Main Methods:
- Utilized latent profile analysis (LPA) on anger metrics from 735 adult CP patients.
- Assessed state/trait anger, anger expression/control, and perceived injustice.
- Examined associations with pain intensity, distribution, interference, behavior, and physical function at baseline and follow-up (n=242).
Main Results:
- Identified four distinct anger profiles based on anger levels and perceived injustice.
- These profiles significantly correlated with pain outcomes at baseline and follow-up, independent of anxiety and depression.
- Profiles with medium-to-high anger and perceived injustice predicted the most severe pain outcomes.
Conclusions:
- Multidimensional anger profiles, especially those involving perceived injustice, are associated with high-impact chronic pain.
- Early identification of these profiles can aid in risk stratification and personalized pain management.
- Tailored, anger-focused interventions are essential for improving long-term outcomes in chronic pain patients.
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