Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Amputation Following Oncologic Endoprosthetic Limb Salvage.

Anticancer research·2026

Same author

What outcomes can be expected after surgical treatment of primary pelvic bone sarcomas in children at referral centers?

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026

Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026

Same author

Complications of PI to PIII hemipelvic resections for intermediate and malignant tumours : a systematic review and meta-analysis.

Bone & joint open·2026

Same author

Perioperative management of Evans Syndrome for free tissue transfer: Case report and recommendations.

JPRAS open·2026

Same author

Analysis of Functional Outcomes and Donor Site Morbidity Following Fibula Flap Harvest in the Skeletally Immature Patient Population.

Plastic and reconstructive surgery·2026

Same journal

Lower-Extremity Reconstruction: Principles, Progress, and Perspectives.

Clinics in plastic surgery·2026

Same journal

Pediatric.

Clinics in plastic surgery·2026

Same journal

Lower Extremity Reconstruction in Acute Burns.

Clinics in plastic surgery·2026

Same journal

Chronic Lower Extremity Wounds: Updates on Lower Extremity Reconstruction in Clinics in Plastic Surgery.

Clinics in plastic surgery·2026

Same journal

Updates in Lower Extremity Reconstruction: Post Sarcoma.

Clinics in plastic surgery·2026

Same journal

Fillet Flaps for Lower Extremity Salvage.

Clinics in plastic surgery·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 10, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Vascularized Bone Grafts in Extremity Reconstruction.

Austin D Chen¹, Alex Antezana¹, David Chi²

¹Division of Plastic and Reconstructive Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.

Clinics in Plastic Surgery

|November 20, 2025

Summary

This summary is machine-generated.

Vascularized bone grafts are crucial for bony reconstruction in various bone loss scenarios, including complex cases and challenging environments. These grafts offer versatile solutions for extremity bone deficits, adaptable as free or pedicled transfers.

Keywords:

Bone graft Extremity reconstruction Vascularized bone graft

More Related Videos

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

Published on: April 26, 2019

Related Experiment Videos

Last Updated: Jan 10, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

Published on: April 26, 2019

Area of Science:

Orthopedic Surgery
Regenerative Medicine
Biomaterials Science

Background:

Vascularized bone grafts are essential for bony reconstruction, particularly in cases of large segmental bone loss.
They are effective for smaller deficits resistant to other treatments or in poorly vascularized areas like those affected by radiation, infection, or avascular necrosis.

Purpose of the Study:

To highlight the critical role and versatility of vascularized bone grafts in orthopedic reconstruction.
To discuss their application in diverse clinical scenarios and anatomical locations.

Main Methods:

Review of current literature and clinical applications of vascularized bone grafting techniques.
Analysis of graft transfer methods, including free and pedicled options.
Consideration of osteochondral and physeal transfers.

Main Results:

Vascularized bone grafts demonstrate significant efficacy in reconstructing both large and small bone defects.
Successful application across the extremities, from distal to proximal locations.
Versatility in transfer methods (free, pedicled) and graft types (osteochondral, physeal).

Conclusions:

Vascularized bone grafts are a vital and adaptable tool for complex bony reconstruction.
Their use is indicated in challenging environments and for various extremity bone deficits.
Effective utilization across different transfer techniques and graft types ensures broad applicability.