Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: consensus of the scientific societies SED, SEEN and SEEP
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View abstract on PubMed
Summary
This summary is machine-generated.Early screening for Type 1 diabetes (T1DM) using autoantibodies can identify presymptomatic individuals, especially those at high genetic risk. This allows for timely interventions to delay disease progression and prevent complications.
Area Of Science
- Endocrinology
- Immunology
- Paediatrics
Background
- Type 1 diabetes (T1DM) is an autoimmune condition often diagnosed late, leading to severe complications like diabetic ketoacidosis, particularly in children.
- Autoantibodies indicate a presymptomatic phase, enabling targeted screening in genetically susceptible populations, such as first-degree relatives.
Purpose Of The Study
- To present consensus recommendations from leading Spanish medical societies (SED, SEEN, SEEP) for screening, staging, and monitoring T1DM in its preclinical stages.
- To establish a unified clinical approach based on current evidence for managing presymptomatic T1DM.
Main Methods
- Development of consensus guidelines by the Spanish Diabetes Society (SED), Spanish Society of Endocrinology and Nutrition (SEEN), and Spanish Society of Paediatric Endocrinology (SEEP).
- Review of available evidence on autoantibody detection, staging criteria, and monitoring protocols for preclinical T1DM.
Main Results
- Identification of specific autoantibodies allows for early detection of T1DM before symptom onset.
- Screening strategies can target high-risk groups, including first-degree relatives of individuals with T1DM.
Conclusions
- Early T1DM identification facilitates personalized care, health education, and potential therapeutic interventions to delay symptomatic progression.
- These recommendations provide a framework for consistent clinical practice in managing preclinical T1DM.
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