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Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
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CT Angiography of the Native Aortic Valve and Paravalvular Disease: From Imaging to Decision-Making

André Vaz1, Lucas Rodrigues Araújo1, Vitor Iglesias Mangolini1

  • 1Instituto do Coração do Hospital de Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas Carvalho de Aguiar, 44, Cerqueira César, São Paulo 05403-900, Brazil (A.V., L.R.A., V.I.M., M.T.d.B.F., P.J.L.A.C., V.d.S.T., H.F.A.A., T.A.D.A., F.T.).

Academic Radiology
|November 20, 2025
PubMed

Insights

Cardiac computed tomography angiography (CTA) is essential for evaluating aortic valve and paravalvular disease. CTA provides detailed anatomical visualization, aiding diagnosis and guiding personalized treatment approaches for various aortic valve conditions.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Cardiac computed tomography angiography (CTA) is increasingly vital for assessing native aortic valve and surrounding structures.
  • Limitations of other imaging modalities highlight the advantages of CTA.

Purpose of the Study:

  • To review the anatomical basis and measurements of the aortic valve using CTA.
  • To delineate valvular phenotypes, including bicuspid morphology.
  • To illustrate CTA's role in characterizing aortic valve diseases.

Main Methods:

  • Review of existing literature and imaging data.
  • Focus on multiplanar and three-dimensional reconstructions from CTA.
  • Analysis of CTA for morphological and functional assessment.

Main Results:

  • CTA offers high spatial and temporal resolution, overcoming acoustic limitations.
  • Detailed anatomical visualization and key measurements are provided by CTA.
  • CTA effectively characterizes aortic stenosis, regurgitation, lesions, and complications.

Conclusions:

  • CTA is a cornerstone for comprehensive aortic valve and paravalvular disease evaluation.
  • CTA supports accurate diagnosis, disease classification, and personalized treatment planning.
  • CTA provides crucial anatomical insights for surgical and interventional guidance.

Keywords:
Aortic valveAortic valve insufficiencyAortic valve stenosisComputed tomographyHeart valve diseases

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