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Continuous Dual Glucose-Ketone Sensing Technology.
Udo Hoss1, Shridhara Alva1, Heather Pryor2
1Abbott Diabetes Care, Alameda, California, USA.
Diabetes Technology & Therapeutics
|November 21, 2025
Summary
Continuous ketone monitoring can improve diabetes management. Abbott’s new dual glucose-ketone sensor offers factory calibration for enhanced accuracy and convenience in detecting diabetic ketoacidosis (DKA).
Area of Science:
- Biomedical Engineering
- Diabetes Technology
- Analytical Chemistry
Background:
- Diabetic ketoacidosis (DKA) is a severe diabetes complication.
- Current ketone monitoring adherence is suboptimal.
- Continuous monitoring offers potential improvements.
Purpose of the Study:
- To describe factory calibration processes for a novel continuous ketone sensor.
- To ensure accuracy, safety, and user convenience of the ketone sensor.
Main Methods:
- Development of a continuous dual glucose-ketone sensor.
- Implementation of factory calibration procedures for the ketone sensor component.
- Simultaneous measurement of interstitial glucose and ketone levels.
Main Results:
- Successful realization of factory calibration processes for the ketone sensor.
- The sensor enables continuous data transmission for glucose and ketone levels.
- Addresses limitations of current ketone monitoring methods.
Conclusions:
- Factory calibration is crucial for the accuracy and usability of continuous ketone sensors.
- This technology has the potential to improve DKA prevention and management.
- Abbott's dual sensor represents a significant advancement in diabetes care technology.

