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Updated: Jan 10, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Bifunctional Aziridines from Photochemically Generated FSO2NH2 for SuFEx Diversification of Alkenes

Avinash Choudhury1, Varun Prabhakar1, Zakary B Newman1

  • 1Department of Chemistry, Texas A & M University, College Station, Texas, 77843, USA.

Angewandte Chemie (International Ed. in English)
|November 21, 2025
PubMed
Summary

Researchers developed a new method to synthesize sulfamoyl fluorides using fluorosulfonyl aziridines. This breakthrough enables versatile alkene diversification and creates novel S(VI)-containing linkages for pharmaceutical applications.

Keywords:
AziridinationRh‐catalyzed nitrene transferScaffold diversificationSuFEx click chemistry

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