Related Experiment Video
Updated: May 2, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
Metamizole-Induced Agranulocytosis: A Case Report
Joana Cartucho1, Ana Ruivo1, Ines Bonito1
1Internal Medicine, Unidade Local de Saúde do Arco Ribeirinho, Barreiro, PRT.
Abstract:
Metamizole, a widely used analgesic and antipyretic, has been associated with rare but potentially life-threatening hematological adverse reactions, such as agranulocytosis. This case report highlights the diagnostic complexity and clinical management of a patient who presented with neutropenic fever and concurrent multidrug-resistant infections, ultimately found to be related to metamizole-induced agranulocytosis. It underlines the importance of considering drug-induced causes in the differential diagnosis of agranulocytosis and stresses the relevance of early identification and prompt discontinuation of the causative agent.
