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Prenatally Detected Sub-amniotic Cysts: Are They Significant?
Nikolaos Antonakopoulos1, Panagiota Tzela2, Georgios Adonakis1
1Department of Obstetrics and Gynecology, School of Health Sciences, University of Patras, Patras, GRC.
Cureus
|November 21, 2025
Summary
Sub-amniotic cysts, identified during pregnancy ultrasound, can enlarge but often have a favorable prognosis. Serial monitoring is recommended for large or multiple cysts to ensure healthy infant outcomes.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Diagnostic Ultrasound
Background:
- Sub-amniotic cysts are rare fluid collections occurring between the amnion and chorion.
- Their identification during routine prenatal screening necessitates understanding their implications.

