Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

512
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
512

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brain MR Elastography Metrics Associated with Alterations in Learning and Memory in People with HIV.

Research square·2026
Same author

Reconstruction of septin higher-order nano-size structures in ovarian cancer cells uncover susceptibility to the septin-targeting small molecule UR214-9.

bioRxiv : the preprint server for biology·2026
Same author

Roles for Phosphatase PP4 in Rhythmicity and Compensation in the Neurospora Circadian System.

bioRxiv : the preprint server for biology·2026
Same author

Local delivery of SBRT and IL-12 to murine PDAC tumors modulates hematopoiesis.

Oncoimmunology·2026
Same author

Sequence Engineering at Non-motif Modulator Residues Yields a Peptide That Effectively Targets a Single PDZ Protein in a Disease-relevant Cellular Context.

Journal of molecular biology·2025
Same author

A Hybrid Model Combining U-Net and Transformers for Joint Segmentation and Beamforming of Plane-wave Ultrasound Images.

Ultrasound in medicine & biology·2025

Related Experiment Video

Updated: Jan 10, 2026

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
12:18

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

12.8K

Merging Single-Track Location Elastographic Imaging with the Frequency Shift Method improves Shear Wave Attenuation

Reem Mislati1, Katia T Iliza1, Scott A Gerber2

  • 1Department of Electrical and Computer Engineering, University of Rochester, Rochester, NY, USA.

Frontiers in Physics
|November 21, 2025
PubMed
Summary
This summary is machine-generated.

A new plane wave single-track location frequency shift (pSTL-FS) method improves shear wave attenuation coefficient (SWA) estimation accuracy, especially in vivo. The pSTL-FS method, using a Gamma distribution, significantly differentiates control from obese mice livers.

Keywords:
Frequency ShiftMurine LiverPoint-Based ApproachShear Wave AttenuationViscoelastic Phantoms

More Related Videos

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment
04:51

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Published on: March 1, 2024

1.4K
Tracking Infiltration Front Depth Using Time-lapse Multi-offset Gathers Collected with Array Antenna Ground Penetrating Radar
07:14

Tracking Infiltration Front Depth Using Time-lapse Multi-offset Gathers Collected with Array Antenna Ground Penetrating Radar

Published on: May 1, 2018

8.1K

Related Experiment Videos

Last Updated: Jan 10, 2026

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
12:18

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

12.8K
Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment
04:51

Author Spotlight: Characterizing Environmental Biofilm Mechanics Using Optical Coherence Elastography and its Applications in Wastewater Treatment

Published on: March 1, 2024

1.4K
Tracking Infiltration Front Depth Using Time-lapse Multi-offset Gathers Collected with Array Antenna Ground Penetrating Radar
07:14

Tracking Infiltration Front Depth Using Time-lapse Multi-offset Gathers Collected with Array Antenna Ground Penetrating Radar

Published on: May 1, 2018

8.1K

Area of Science:

  • Ultrasound Elastography
  • Biomedical Ultrasound
  • Medical Imaging

Background:

  • The frequency shift (FS) method is standard for estimating shear wave attenuation coefficient (SWA), but susceptible to measurement noise, particularly in vivo.
  • Existing methods like FS and AMUSE have limitations in accuracy and sensitivity to noise.
  • The choice of distribution (Gaussian vs. Gamma) for the shear wave spectrum can impact SWA estimation.

Purpose of the Study:

  • To evaluate a novel plane wave single-track location frequency shift (pSTL-FS) method for improved SWA estimation.
  • To compare the accuracy and robustness of pSTL-FS against existing methods (FS, AMUSE) using phantoms and in vivo murine livers.
  • To determine the optimal distribution (Gaussian or Gamma) for shear wave spectrum analysis in SWA estimation.

Main Methods:

  • Development and application of the pSTL-FS method combining plane wave imaging with FS principles.
  • Comparative analysis of pSTL-FS (Gamma/Gaussian) against FS (Gamma/Gaussian) and AMUSE methods.
  • Validation using calibrated phantoms with known SWA coefficients (via mechanical testing) and in vivo studies on control and obese murine livers.

Main Results:

  • pSTL-FS (Gamma) demonstrated high accuracy (84.69%–97.55%) in phantom studies, significantly outperforming FS methods.
  • In murine liver studies, pSTL-FS (Gamma) revealed the highest significant difference between control and obese groups (p < 0.0001).
  • The Gamma distribution proved more representative of the shear wave frequency spectrum in murine livers compared to the Gaussian distribution.

Conclusions:

  • The combined pSTL-FS method offers more robust SWA coefficient estimates than the standard FS method, especially in noisy in vivo conditions.
  • pSTL-FS, particularly with a Gamma distribution, enhances the ability to detect pathological differences, such as in obese murine livers.
  • The findings support the adoption of pSTL-FS with a Gamma distribution for accurate and sensitive SWA measurements in biomedical applications.