Related Experiment Video For artificial intelligence
Updated: Jan 10, 2026
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
Published on: March 3, 2023
Artificial intelligence for ovarian cancer diagnosis via ultrasound: a systematic review and quantitative assessment
Igor Garcia-Atutxa1,2, Francisca Villanueva-Flores2, Ekaitz Dudagotia Barrio3
1Escuela Politécnica Superior, Universidad Católica de Murcia (UCAM), Murcia, Spain.
Background:
Early and accurate detection of ovarian cancer (OC) remains clinically challenging, prompting exploration of artificial intelligence (AI)-based ultrasound diagnostics. This systematic review and meta-analysis critically evaluate diagnostic accuracy, methodological rigor, and clinical applicability of AI models for ovarian mass classification using B-mode ultrasound.
Methods:
A systematic literature search following PRISMA guidelines was conducted in PubMed, IEEE Xplore, and Scopus up to December 2024. Eligible studies included AI-based ovarian mass classification using B-mode ultrasound, reporting accuracy, sensitivity, specificity, and/or area under the ROC curve (AUC). Data extraction, quality assessment (PROBAST), and meta-analysis (random effects) were independently performed by two reviewers. Heterogeneity sources were explored.
Results:
From 823 identified records, 44 studies met inclusion criteria, covering over 650,000 images. Pooled performance metrics indicated high accuracy (92.3%), sensitivity (91.6%), specificity (90.1%), and AUC (0.93). Automated segmentation significantly outperformed manual segmentation in accuracy and sensitivity, demonstrating standardization benefits and reduced observer variability. Dataset size minimally correlated with performance, highlighting methodological rigor as a primary determinant. No specific AI architecture consistently outperformed others. Substantial methodological heterogeneity and frequent risk-of-bias issues (limited validation, small datasets) currently limit clinical translation.
Conclusion:
AI models show promising diagnostic performance for OC ultrasound imaging. However, addressing methodological challenges, including rigorous validation, standardized reporting (TRIPOD-AI, STARD-AI), and prospective multicenter studies, is essential for clinical integration. This review provides clear recommendations to enhance clinical translation of AI-based ultrasound diagnostics.
