Single Incision Laparoscopic Local Resection for Gastric Gastrointestinal Stromal Tumors Compared to Multiport Laparoscopic Local Resection: A Single-Center Retrospective Study

Gastric gastrointestinal stromal tumors are generally treated via local resection. Single-incision laparoscopic surgery has recently been reported as minimally invasive surgery. This study aimed to evaluate the safety and short-term and long-term outcomes of single incision laparoscopic local resection compared with those of multiport laparoscopic local resection for gastric gastrointestinal stromal tumors with extraluminal growth.

Laparoscopic local resection of the stomach was used for 71 patients with gastric gastrointestinal stromal tumors between January 2010 and March 2025 at Wakayama Medical University Hospital. Short-term and long-term outcomes were compared between those who underwent single incision laparoscopic local resection and those who underwent multiport laparoscopic local resection.

Single incision laparoscopic local resection and multiport laparoscopic local resection were performed for 24 and 47 patients, respectively. Patient characteristics including tumor location and tumor size were not significantly different between the two groups. Further, there was no significant difference in operation time, blood loss, time to oral intake, postoperative hospital stays, or risk classification of recurrence. The postoperative max CRP of the single incision laparoscopic local resection group was significantly lower than that of the multiport laparoscopic local resection group. No postoperative complications were found in those who underwent single incision laparoscopic local resection. There was no recurrence in those who underwent single incision laparoscopic local resection, but two patients who underwent multiport laparoscopic local resection had recurrences: one with liver metastasis, the other with peritoneal metastasis.

Single incision laparoscopic local resection is considered to be a safe and feasible surgical technique for gastric gastrointestinal stromal tumors with extraluminal growth. Furthermore, long-term outcomes were also acceptable.