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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Longitudinal Studies01:26

Longitudinal Studies

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Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
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Longitudinal Research02:20

Longitudinal Research

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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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Data Collection II01:29

Data Collection II

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The nursing history captures and records the patient's health status, so that a care plan evolves to meet the patient's individual needs. The nursing health history is a part of the initial assessment. A comprehensive history covers all health dimensions and plays a significant role in the assessment process. A comprehensive history includes the patient's biographical information, reasons for seeking health care, expectations, present and past health history, medications, and...
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Observational Studies01:11

Observational Studies

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Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
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Related Experiment Video

Updated: Jan 10, 2026

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease

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Dementia Data Landscape 1. Cohorts.

Amelia Morgan1, Conor Durkin1, Benjamin Tari1

  • 1Dementias Platform UK, Department of Psychiatry, University of Oxford, Oxford, UK.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|November 21, 2025
PubMed
Summary
This summary is machine-generated.

This study identified 883 dementia cohorts worldwide, revealing extensive data for reuse. Key improvements needed include metadata transparency and data accessibility, especially for underrepresented regions like the Global South.

Keywords:
Alzheimer's diseaseC‐Survclinical cohortcohort studydata accessdata characterizationdata landscapedata repurposedata reusedataset discoverydementiametadatapopulation cohort

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Last Updated: Jan 10, 2026

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Using Retinal Imaging to Study Dementia
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Area of Science:

  • Neuroscience
  • Public Health
  • Data Science

Background:

  • Maximizing complex health data is vital for accelerating dementia discovery and translational research.
  • Repurposing existing datasets offers a rapid and cost-effective approach to progress.
  • Strengthening health cohort infrastructure is essential for efficient data management.

Purpose of the Study:

  • To explore the global dementia cohort landscape and identify cohorts relevant for dementia research.
  • To assess the availability and accessibility of dementia-related data for future research.
  • To highlight areas for improvement in health cohort infrastructure and data management.

Main Methods:

  • Searched PubMed for publications on dementia cohorts (1970-2024) and international dementia data platforms.
  • Utilized a template aligned with the C-Surv data model to summarize cohort details and measurements.
  • Identified 883 dementia cohorts, categorizing them into population-based and clinical cohorts.

Main Results:

  • Identified 883 dementia cohorts (558 population, 325 clinical) globally between 1970 and 2024.
  • Found that 74% of cohorts indicated data availability, but metadata reporting and quality varied significantly.
  • Only 45% of cohorts were discoverable through existing data platforms, with the Global South being underrepresented.

Conclusions:

  • Extensive global dementia data is available for repurposing, offering significant opportunities for research.
  • Priority areas for improvement include enhancing metadata transparency and data accessibility.
  • The developed online landscape tool facilitates strategic discovery and reuse of dementia data.