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Sickle Cell Trait Is a Risk Factor for Another Form of Altitude Illness.

Grégoire P Millet1, Philippe Connes2,3

  • 1Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

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|November 21, 2025
PubMed
Summary
This summary is machine-generated.

Sickle cell trait may be a risk factor for a serious altitude illness beyond the commonly known ones. This finding highlights a potential concern for individuals with sickle cell trait when exposed to high altitudes.

Area of Science:

  • Altitude Medicine
  • Hematology

Background:

  • Acute mountain sickness, high-altitude pulmonary edema, and high-altitude cerebral edema are well-documented altitude illnesses.
  • The potential risks associated with high altitude exposure for individuals with specific genetic conditions remain an area for further investigation.
Keywords:
dehydrationhyposthenuriasickle cell trait

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