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Hypertensive phase after a novel small-lumen non-valved drainage device: predictive factors and two-year outcomes

Francesc Franquesa-Garcia1,2, Sara Labay-Tejado3, Néstor Ventura-Abreu4

  • 1Department of Ophthalmology, Hospital Germans Trias i Pujol, Carretera de Canyet s/n, 08916, Barcelona, Spain.

Japanese Journal of Ophthalmology
|November 21, 2025
PubMed

Insights

The hypertensive phase after glaucoma drainage device implantation does not affect long-term surgical success. Younger age and elevated early postoperative IOP are risk factors for this phase.

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Medical Devices

Background:

  • The hypertensive phase (HP) is a common challenge after glaucoma drainage device (GDD) implantation.
  • Understanding HP risk factors and its impact on surgical outcomes is crucial for patient management.

Purpose of the Study:

  • To evaluate risk factors, clinical features, and the correlation of HP with efficacy in patients receiving a Paul glaucoma implant (PGI).

Main Methods:

  • Retrospective cohort study of 83 eyes (71 patients) implanted with PGI.
  • Intraocular pressure (IOP) monitored for 2 years postoperatively.
  • Analysis of HP occurrence, risk factors, and correlation with success criteria.

Main Results:

  • Hypertensive phase observed in 27.7% of cases.
  • Younger age and elevated 1-month postoperative IOP identified as independent risk factors.
  • Higher IOP in HP group at 1 week and 1-6 months, with no significant difference after 12 months.

Conclusions:

  • Hypertensive phase occurrence with PGI does not appear to impact surgical success beyond 12 months.
  • Further research is needed to elucidate HP mechanisms and clinical significance.
Abstract

Keywords:
Glaucoma drainage deviceHypertensive phaseIntraocular pressurePaul glaucoma implantSurgical success

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