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Updated: Jan 10, 2026

Author Spotlight: Enhancing Vascular Function and Physical Capacity in Cardiovascular Disease Through Novel Interventions and NIRS Technology
Published on: March 22, 2024
Advancing chronic wound care with near-infrared spectroscopy imaging: clinical applications, measurement parameters,
Alisha Oropallo1, Alex G Ortega-Loayza2, Holly Korzendorfer3
1Department of Vascular Surgery, Donald and Barbara Zucker School of Medicine, Hofstra/Northwell, Hempstead, NY, USA; Feinstein Institutes for Medical Research, Manhasset, NY, USA; Comprehensive Wound Healing Center, Department of Vascular and Endovascular Surgery, Northwell Health, Lake Success, NY, USA; Wound Care Collaborative Community, Orlando, FL, USA.
Background:
Chronic wound management is a global health care challenge affecting patient morbidity and quality of life while presenting a substantial economic burden. A critical limitation in effective wound care is the inability to accurately assess microvascular tissue health in real time. This review of near-infrared spectroscopy (NIRS) imaging and its use in wound care emphasizes relevant clinical end points and explores key measurement parameters assessed via NIRS imaging.
Objective:
To identify, describe, and illustrate NIRS imaging modalities and measurement parameters, and their clinical applications.
Results:
Clinical studies demonstrated that NIRS imaging can effectively detect poor wound healing early, facilitating timely interventions. Changes in parameters such as oxygenated hemoglobin, deoxygenated hemoglobin, and tissue oxygen saturation have shown strong correlations with wound healing progress, enabling clinicians to make more informed decisions.
Conclusion:
NIRS imaging advances wound management by providing real-time, noninvasive, and objective data on tissue oxygenation and perfusion. NIRS imaging may objectively complement the standard percentage area reduction assessments during the wound treatment process.

