Related Experiment Video
Updated: Jan 10, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Ultra-low-dose computed tomography (CT) protocol for guiding cryoablation in treating a T1a renal cell carcinoma
1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Aim:
The purpose of this study was to evaluate the utility of an ultra-low-dose computed tomography (CT) protocol in guiding cryoablation and oncologic outcomes in the treatment of small renal cell carcinoma (RCC).
Materials And Methods:
CT-guided cryoablation using 120 kvp, 50 mA and 2.4 mGy was performed in 30 patients with 30 biopsy-proven T1a-RCCs between January 2023 and January 2024. Cryoablation procedures consisted of planning, targeting, monitoring, and survey phases. The dose-length product (DLP), estimated effective dose (eED), number of scans, scan ranges, total current, and exposure time of cryoablation phases were presented. The one-year local tumour progression (LTP)-free survival rate was calculated by Kaplan-Meier analysis. Nonparametric ANOVA with Dunn's multiple comparisons was used to compare radiation dose and CT parameters.
Results:
The median DLP and eED per session were 442.3 mGy·cm (287.1-897.8 mGy·cm) and 6.6 mSv (4.3-13.5 mSv), respectively. The DLP, eED, number of scans, total current, and exposure time in the targeting and monitoring phases were significantly higher than those in the planning and survey phases (P < 0.001). The scan ranges in the targeting and monitoring phases were smaller than those in the planning and survey phases (P < 0.001). The one-year LTP-free survival rate was 96.7% (29/30).
Conclusion:
Ultra-low-dose CT-guided cryoablation contributes to significant dose reduction without compromising oncologic outcomes of small RCCs.
