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Updated: Jan 10, 2026
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Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
Published on: November 30, 2022
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Community and bioethicists' perspectives on iPSC research with biobanked samples collected using broad consent
P A Ikhane1, T Yusuf2, O Adeyemo2
1Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA; Department of Research, Center for Bioethics and Research, Ibadan, Nigeria; Department of Bioethics and Medical Humanities, University of Ibadan, Ibadan, Nigeria.
Stem Cell Reports
|November 21, 2025
Summary
Community engagement and transparent governance are key for ethical use of biobanked samples, especially for induced pluripotent stem cells (iPSCs). Broad consent is supported when it ensures benefit sharing and sustained community involvement in research.
Area of Science:
- Bioethics
- Stem Cell Research
- Genomic Biobanking
Background:
- Anonymized, biobanked samples for induced pluripotent stem cells (iPSCs) raise ethical concerns.
- Existing ethical frameworks may not adequately address novel research applications of stored samples.
Purpose of the Study:
- To investigate community and bioethicist perspectives on ethical issues surrounding the use of biobanked samples.
- To inform best practices for the collection and utilization of samples for induced pluripotent stem cells (iPSCs) research.
Main Methods:
- Qualitative study involving community members and bioethicists.
- Focus on perspectives related to the Yoruba Resident in Ibadan, Nigeria (YRI) HapMap sample collection.
Main Results:
- Support for broad consent, commercial use, and benefit sharing for biobanked samples.
- Emphasis on sustained community engagement and local researcher involvement, particularly for novel or long-term research.
- Community support for broad consent is contingent on transparent governance and reciprocal benefit.
Conclusions:
- Sustained community engagement, transparent governance, and practical benefit-sharing mechanisms enhance the ethical acceptability of broad consent for biobanked samples.
- Ethical considerations for biobanked samples require ongoing dialogue and adaptation, especially for induced pluripotent stem cells (iPSCs) research.
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