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Open Questions in Particle Therapy for Head and Neck Cancer
Romelie Rieu1, Dawn Carnell2, Melvin L K Chua3
1Department of Head and Neck Oncology, The Royal Marsden NHS Foundation Trust, London, UK; The Institute of Cancer Research, London, UK.
Abstract:
Particle therapy's distinct depth-dose profile may reduce normal-tissue dose while maintaining intensity-modulated radiotherapy-comparable target coverage, thereby potentially lowering treatment-related toxicity and/or enabling safe dose escalation. We consider uncertainties in adult head and neck particle therapy across delivery/verification, radiobiology, and patient selection.
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