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A multi-head YOLOv12 with self-supervised pretraining for urinary sediment particle detection
Mehdi Alizadeh1, Ali Karimi2, Mohammad Javad Barikbin2
1Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Scientific Reports
|November 21, 2025
Summary
This study introduces a new deep learning model for urine sediment analysis, improving accuracy and efficiency. The AI system effectively identifies various particles, aiding in diagnosing kidney and urinary disorders.
Area of Science:
- Medical Diagnostics
- Artificial Intelligence
- Computer Vision
Background:
- Manual urine sediment analysis is crucial but suffers from subjectivity and time constraints.
- Existing automated methods lack the granularity for comprehensive particle classification.
- Developing an objective and efficient automated system is vital for clinical practice.
Purpose of the Study:
- To develop a novel deep learning method for automated and reliable urine sediment analysis.
- To enable simultaneous, fine-grained classification of diverse urine sediment particles.
- To overcome limitations of manual analysis and prior automated techniques.
Main Methods:
- Utilized a multi-head YOLOv12 architecture with self-supervised pretraining.
- Implemented Slicing Aided Hyper Inference (SAHI) for advanced object detection.
- Created a large-scale dataset (OpenUrine) with 790 labeled and 5640 unlabeled images across 39 categories.
Main Results:
- Achieved 76.59% precision and 64.15% mean Average Precision (mAP) on a 39-class dataset.
- Demonstrated competitive detection accuracy, particularly for small and low-contrast objects.
- The six specialized detection heads enabled comprehensive particle classification.
Conclusions:
- The proposed deep learning method offers a significant advancement in automated urine sediment analysis.
- This AI-driven approach enhances diagnostic capabilities for renal and urinary disorders.
- The model's performance indicates its potential for clinical application and improved patient outcomes.
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