Hybrid deep learning framework for cardiovascular disease diagnosis and prognosis using GAN, LSTM, GRU, VARMA, and

Vijayasimha A1, Avanija J2

  • 1Department of Computer Science, School of Computing, Mohan Babu University, Tirupati, 517502, Andhra Pradesh, India. vijaysimha212@gmail.com.

Scientific Reports
|November 21, 2025
PubMed

Insights

This study introduces a novel deep learning method for early cardiovascular disease (CVD) diagnosis using advanced AI models. The approach significantly enhances diagnostic accuracy, improving patient outcomes and treatment strategies.

Area of Science:

  • Artificial Intelligence in Medicine
  • Cardiovascular Disease Diagnostics
  • Medical Image Analysis

Background:

  • Cardiovascular diseases (CVDs) represent a significant global health burden, necessitating accurate and timely diagnosis.
  • Medical image analysis is crucial for effective CVD diagnosis and prognosis.
  • Existing diagnostic methods require improvement for enhanced accuracy and efficiency.

Purpose of the Study:

  • To propose a novel deep learning framework for improving cardiovascular disease diagnosis.
  • To leverage Generative Adversarial Networks (GANs), Long Short-Term Memory (LSTM), Gated Recurrent Units (GRUs), Vector Auto Regressive Moving Average (VARMA), and Deep Dyna Q Network for enhanced analysis.
  • To develop a robust system for real-time CVD diagnosis and treatment policy optimization.

Main Methods:

  • Utilized GANs to generate synthetic medical images for training sequential models (LSTM, GRU).
  • Employed VARMA to model temporal dependencies within time-series medical data.
  • Implemented Deep Dyna Q Network for learning optimal diagnostic and treatment policies.

Main Results:

  • The proposed deep learning approach achieved 95% accuracy and high sensitivity in diagnosing CVDs.
  • Demonstrated superior performance compared to state-of-the-art methods in clinical scenarios.
  • The model effectively analyzed sequential medical image time series data.

Conclusions:

  • The novel deep learning framework shows significant potential for improving CVD diagnosis and treatment.
  • This approach can enhance cardiovascular medication effectiveness and potentially extend patient lifespan.
  • The system offers a promising solution for real-time clinical applications in cardiovascular care.

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