Radiotherapy of sinonasal cancers: 2025 update

Area of Science:

• Oncology
• Radiotherapy
• Head and Neck Cancer

Background:

• Sinonasal cancers represent 3-5% of head and neck malignancies, encompassing various histologic types.
• These rare tumors present with non-specific symptoms and have a heterogeneous prognosis.
• Expert networks like the French expert network for rare head and neck cancers (Refcor) coordinate care and multidisciplinary tumor boards.

Purpose of the Study:

• To provide an updated overview of the French society for radiation oncology (SFRO) recommendations for radiotherapy in sinonasal cancers.
• To guide clinicians on treatment planning, techniques, dose, and volume specifications for these rare tumors.
• To emphasize the importance of careful target volume delineation in locoregional radiotherapy for sinonasal cancers.

Main Methods:

• Review of current Société française de radiothérapie oncologique (SFRO) guidelines.
• Incorporation of expert pathological review and multidisciplinary tumor board recommendations.
• Focus on specific considerations for radiotherapy in sinonasal cancers, including histologic subtype, grade, and nodal involvement.

Main Results:

• The article details updated recommendations for radiotherapy indications in sinonasal cancers.
• It covers crucial aspects of treatment planning, including target volume delineation.
• Guidance is provided on radiotherapy techniques, dose and volume specifications, and post-treatment follow-up.

Conclusions:

• Radiotherapy plays a critical role in managing sinonasal cancers.
• Tailored treatment planning considering tumor characteristics is essential for effective radiotherapy.
• Adherence to updated SFRO recommendations can optimize therapeutic outcomes for patients with sinonasal cancers.