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Study of prognostic factors for complicated acute rhinosinusitis in children
Abdulaziz Alghamdi1, Karine Aubry2, Lucie Cussinet2
1Limoges University Hospital Center, ENT Department, 2 Av. Martin Luther King, 87000, Limoges, France; King Abdulaziz University, ENT Department, Jeddah, Saudi Arabia.
Insights
Asthma, NSAID use, and elevated CRP levels predict complications in pediatric acute bacterial rhinosinusitis. Early imaging and clinical vigilance are recommended for these high-risk children.
Area of Science:
- Pediatric Infectious Diseases
- Otolaryngology
Background:
- Acute bacterial rhinosinusitis is common in children, with potential for serious complications.
- Predictors for complicated pediatric rhinosinusitis are not well-defined.
- Identifying risk factors is crucial for timely intervention.
Purpose of the Study:
- To identify predictors of complications in pediatric acute bacterial rhinosinusitis.
- To evaluate factors associated with treatment failure.
- To assess predictors of severe complications.
Main Methods:
- Retrospective study of 109 children hospitalized for acute sinusitis (2010-2020).
- Data collected: demographics, medical history, clinical presentation, labs, imaging.
- Multivariate logistic regression used for statistical analysis.
Main Results:
- Asthma and prior NSAID use increased complication risk.
- Elevated C-reactive protein (CRP) and lymphopenia indicated severity.
- Anaerobic Streptococci were linked to more severe cases.
Conclusions:
- Asthma, NSAID use, and high CRP levels are reliable indicators of complications.
- Findings suggest increased clinical vigilance and early imaging are warranted.
- These factors aid in risk stratification for pediatric rhinosinusitis.
Introduction:
Acute bacterial rhinosinusitis is frequently seen in children. While complications are uncommon, they can be serious. Risk factors associated with complicated cases remain poorly defined. This study aimed primarily to identify predictors of complications in pediatric rhinosinusitis. Secondary objectives included evaluating factors associated with treatment failure and the occurrence of severe complications.
Methods:
We conducted a retrospective study of all children hospitalized for acute sinusitis at Limoges University Hospital between 2010 and 2020. Data on demographics, medical history, clinical presentation, laboratory tests, and imaging were collected. Statistical analyses included multivariate logistic regression.
Results:
A total of 109 patients were included. Asthma and prior use of NSAIDs were associated with higher risk of complications. Elevated CRP and lymphopenia were significant biological indicators of severity. Anaerobic Streptococci were more often associated with severe cases.
Conclusion:
Asthma, NSAID use, and high CRP levels appear to be reliable indicators of complications in pediatric acute bacterial rhinosinusitis. These findings support the need for clinical vigilance and early imaging in such cases.
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