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Updated: Jan 10, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
Published on: January 20, 2019
CEBPB emerges as a key regulatory factor in human cancers through diverse molecular mechanisms and clinical
Anbang He1, Cunjin Wu2, Dan Xia3
1Department of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311121, China. heanbang323@163.com.
Abstract:
CCAAT/enhancer-binding protein beta (CEBPB) is a critical transcription factor for cellular differentiation, inflammation, and metabolism. Recent studies have highlighted its dual role in tumorigenesis, functioning as both an oncogenic driver and tumor suppressor across diverse malignancies. This review synthesizes advances in understanding CEBPB's contributions to tumorigenesis, tumor progression, immune evasion, and therapy resistance, emphasizing its potential as a cancer-specific molecular biomarker in cancer diagnosis, prognosis and treatment.
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