Related Experiment Video
Updated: Jan 10, 2026

Three-Dimensional Reconstruction of Orbital Fractures
Published on: May 16, 2025
Practice Patterns in the Management of Preseptal and Orbital Cellulitis: A National Survey
Emily Lan-Vy Nguyen1, Carsten Krueger2, Sanjay Mahant1,3,4,5
1The Hospital for Sick Children, Toronto, Ontario, Canada.
Insights
Clinical practice for pediatric preseptal and orbital cellulitis varies widely across Canadian hospitals. This study highlights the need for standardized diagnostic testing, antibiotic use, and management guidelines.
Area of Science:
- Pediatric infectious diseases
- Ophthalmology
- Emergency medicine
Background:
- Preseptal and orbital cellulitis are common pediatric infections.
- Current management strategies lack standardization across Canadian healthcare facilities.
Purpose of the Study:
- To delineate current clinical practice patterns for pediatric preseptal and orbital cellulitis.
- To identify variations in diagnostic testing, antibiotic treatment, hospitalization, subspecialty consultation, and discharge recommendations.
Main Methods:
- A cross-sectional survey was distributed to pediatric hospitalists and emergency department physicians across Canadian hospitals.
- The survey assessed site-level clinical management practices.
- Data were collected through the Canadian Pediatric Inpatient Research Network and analyzed descriptively.
Main Results:
- 32 out of 40 contacted hospitals responded (80% response rate).
- Complete blood count and C-reactive protein were the most common ED tests. CT scans were more frequently ordered in children's hospitals.
- Ophthalmology, otolaryngology, and infectious diseases were frequently consulted at children's hospitals. Antibiotic choices varied for both preseptal and orbital cellulitis.
Conclusions:
- Significant variability exists in diagnostic workups, subspecialty referrals, and empirical antibiotic choices for pediatric cellulitis.
- The findings underscore a critical need for developing a standardized clinical practice guideline to ensure consistent patient care.
Objective:
To describe clinical practice patterns in diagnostic testing, antibiotic treatment, hospitalization, subspecialty consultation, and discharge recommendations for children with preseptal and orbital cellulitis across Canadian hospitals.
Methods:
A cross-sectional survey of pediatric hospitalists and pediatric emergency department (ED) physicians was conducted. The survey was distributed through the Canadian Pediatric Inpatient Research Network and completed by hospital representatives. Site-level clinical management specific to clinician was assessed. Data were analyzed descriptively.
Results:
Of 40 hospitals contacted (17 children's and 23 community hospitals), 32 responded (80%; 13 children's hospitals, 19 community hospitals). The most ordered tests in the ED were complete blood count (81.9%) and C-reactive protein (CRP; 81.9%). When not ordered in the ED, 20 (62.5%) pediatric inpatient services ordered CRP and 4 (12.5%) ordered erythrocyte sedimentation rate. For admitted children, computed tomography scans were ordered always or frequently by 46.2% of children's hospital pediatricians and 5.3% of community hospital pediatricians. Ophthalmology (n = 11, 84.6%), otolaryngology (n = 9, 69.2%), and infectious diseases (n = 6, 46.2%) were frequently consulted at children's hospitals. Children with preseptal cellulitis not requiring admission were usually discharged home on oral cephalexin, whereas 2 sites recommended intravenous (IV) ceftriaxone. All children admitted with orbital cellulitis received IV antibiotics initially, most commonly a third-generation cephalosporin with antianerobic and antistaphylococcal agents or a third-generation cephalosporin with an antistaphylococcal agent.
Conclusions:
There is limited consensus on diagnostic tests, subspeciality consultation, and empirical antibiotic therapy for preseptal and orbital cellulitis. This survey provides insight into health system-level usage that highlights the need to develop a clinical practice guideline to help standardize management.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Tonsillitis II: Management

