Practice Patterns in the Management of Preseptal and Orbital Cellulitis: A National Survey

Emily Lan-Vy Nguyen1, Carsten Krueger2, Sanjay Mahant1,3,4,5

  • 1The Hospital for Sick Children, Toronto, Ontario, Canada.

Hospital Pediatrics
|November 23, 2025
PubMed

Insights

Clinical practice for pediatric preseptal and orbital cellulitis varies widely across Canadian hospitals. This study highlights the need for standardized diagnostic testing, antibiotic use, and management guidelines.

Area of Science:

  • Pediatric infectious diseases
  • Ophthalmology
  • Emergency medicine

Background:

  • Preseptal and orbital cellulitis are common pediatric infections.
  • Current management strategies lack standardization across Canadian healthcare facilities.

Purpose of the Study:

  • To delineate current clinical practice patterns for pediatric preseptal and orbital cellulitis.
  • To identify variations in diagnostic testing, antibiotic treatment, hospitalization, subspecialty consultation, and discharge recommendations.

Main Methods:

  • A cross-sectional survey was distributed to pediatric hospitalists and emergency department physicians across Canadian hospitals.
  • The survey assessed site-level clinical management practices.
  • Data were collected through the Canadian Pediatric Inpatient Research Network and analyzed descriptively.

Main Results:

  • 32 out of 40 contacted hospitals responded (80% response rate).
  • Complete blood count and C-reactive protein were the most common ED tests. CT scans were more frequently ordered in children's hospitals.
  • Ophthalmology, otolaryngology, and infectious diseases were frequently consulted at children's hospitals. Antibiotic choices varied for both preseptal and orbital cellulitis.

Conclusions:

  • Significant variability exists in diagnostic workups, subspecialty referrals, and empirical antibiotic choices for pediatric cellulitis.
  • The findings underscore a critical need for developing a standardized clinical practice guideline to ensure consistent patient care.
Abstract